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Patients with very high or very low blood-pressure levels along with depressive symptoms may be at risk for serious CV events, such as MI, heart failure, or even death, suggests new research[1].

A study of more than 35,000 patients in Scotland showed an 83% higher relative risk (RR) for CV events in those with both depression and high systolic BP vs those without both conditions. And those with depression and very low systolic BP had a 36% higher RR for CV events.

Interestingly, there were no associations found between CV-event risk and diastolic blood pressure plus depression.

http://www.medscape.com/viewarticle/850253