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Doctors gathering here for HYPERTENSION 2014 <http://www.medscape.com/viewcollection/33154> , the joint European Society of Hypertension and International Society of Hypertension meeting, are turning with renewed attention to the question: just how many patients truly have "resistant" hypertension? Even more pressing, they say, is establishing once and for all what is the best way to get blood pressure down in these patients.
Those questions are on everyone"s minds following the disappointing results of the SYMPLICITY 3 <http://www.medscape.com/viewarticle/822740> trial of renal denervation, where the newer interventional therapy was no better than medical care in patients deemed to have resistant hypertension at the study outset.
Elsewhere, Dr Giuseppe Mancia (University of Milano-Bicocca, Milan, Italy) presented Italian data tackling patient noncompliance at a population level, looking at the number of patients who actually refilled drug prescriptions within 90 days. Mancia and colleagues have been tracking these data in the Lombardy region of Italy for many years, publishing several papers addressing this topic. Consistently, the number of patients who discontinue their drugs (according to pharmacy nonrenewals) hovers at around two-thirds, he showed. "I think we can all agree, adherence to treatment may have a far greater impact on the health of the population than any improvement in specific medical treatments," Mancia said.
 
http://www.medscape.com/viewarticle/826771?nlid=59344_2565&src=wnl_edit_medp_card&uac=125645DR&spon=2#2