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 The Long-Term Effect of Goal Directed Weight Management on an Atrial Fibrillation Cohort (LEGACY) study included more than 300 adults with AF and a body-mass index (BMI) of at least 27 kg/m2. Results showed that the subgroup that had at least a 10% weight loss 1 year after completing a physician-led management program had more reductions in severe symptoms of AF than the groups who lost less weight. They were also six times more likely to achieve arrhythmia-free survival.

The findings were presented at a late-breaking clinical-trial session here at the American College of Cardiology (ACC) 2015 Scientific Sessions and simultaneously published in the Journal of the American College of Cardiology.

Pathak R, et al. Long-term effect of goal directed weight management in an atrial fibrillation cohort: A long-term follow-up study (LEGACY Study). J Am Coll Cardiol 2015; DOI:101016/jacc.2015.03.002. Available at: http://content.onlinejacc.org/journal.aspx.