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Depression Common Among Patients With Stable Angina Also

While research has shown that depression is prevalent among patients with MI, little has been published about depression among patients with chronic stable angina, but a new study sheds light on this aspect of depression[4]. Dr Natalie Szpakowski (Shulich Heart Center, Sunnybrook Health Sciences Center, Toronto, ON) and colleagues analyzed data from the Cardiac Care Network of Ontario (CCN) to evaluate the association between depression after angiography for suspected CAD and subsequent clinical outcomes.

The results were published online October 4, 2016 in Circulation: Cardiovascular Quality and Outcomes.

The researchers found that among a cohort of 22,917 patients between October 1, 2008 and September 30, 2013, depression after diagnosis of stable angina occurred in 18.8% during follow-up of 1084 days. They found that the primary predictor of depression was remote episode of depression within the previous 10 years (HR1.88, 95% CI 1.75–2.02). Other strong predictors were female sex and more angina.

Patients with depression had almost a twofold risk of death (HR 1.83, 95% CI 1.62–2.07) and a higher risk of MI (HR 1.36, 95% CI 1.10–1.67) compared with patients who were not depressed.

"Our study is unique in that it evaluated angina patients at a population level using a contemporary provincewide registry," the researchers wrote.

http://www.medscape.com/viewarticle/870097