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Brisk Walking Can Help in Hypertrophic Cardiomyopathy: RESET-HCM

The first randomized controlled trial to examine the feasibility of moderate exercise, such as brisk walking, for patients with hypertrophic cardiomyopathy provides reassurance that this type of exercise can improve cardiovascular fitness. There were no adverse events, but the trial was not designed to establish long-term safety, researchers caution.

Specifically, in the Randomized Exploratory Study of Exercise Training in Hypertrophic Cardiomyopathy (RESET-HCM) of 136 patients with the inherited disease, patients who followed a 4-month, structured but unsupervised moderate-intensity exercise-training program had a small but significant increase in exercise capacity compared with their peers who kept their usual exercise habits.The moderate regular exercise did not trigger ventricular arrhythmia and sudden cardiac arrest or appropriate defibrillator shock, and none of the patients died.

The study was presented the findings at the American College of Cardiology (ACC) 2017 Scientific Sessions, which were simultaneously published online in the Journal of the American Medical Association.

As there have been no randomized trials to help inform treatment decisions, many physicians caring for patients with hypertrophic cardiomyopathy recommend extremely conservative physical-activity restrictions, and many patients are fearful of doing any exercise at all.